A Guide to Nystatin

Anti fungal Cream

Nystatin is a popular antibiotic treatment for fungal infections at the mouth, lips and skin. It is manufactured as a pill, oral suspension, cream or ointment. It also comes in lozenges for the mouth infection. Doctors recommend it as an angular cheilitis cure.

There are several brand names of this type of antibiotic in the drugstores such as Mycostatin, Mycostatin Filmlok, Mycostatin Pastilles, Nystatin Ointment, Nystat-Rx, Nystop and Pedi-Dri.

How Nystatin works

As an anti fungal, it kills fungi by interfering with glucose import. Like all cells, fungi surround a membrane but because the glucose is big to enter through the membrane, special proteins import the glucose. This is where this anti fungal works. It disrupts the glucose from getting into the cells. Because glucose uses fungi for energy, overtime glucose reserves will be depleted and will cause the cells to atrophy and die.

Before applying the cream or ointment, make sure that you have thoroughly washed and dried the affected area. Then apply a small amount and gently rub on the lesion. Avoid getting the cream or ointment into your eyes.

Side effects

Follow doctor’s prescribed daily application. Do not use it more than what is recommended. The frequency of application will not speed up healing; at worst, it will lead to the side effects.

For topical antibiotic, side effects are burning or itching sensation, rash and eczema including pain when applying the cream or lotion. A life-threatening skin side effect, although occurring extremely infrequent, is Stevens-Johnson syndrome where patients experience flu-like symptoms preceding red skin rash over a large area of the skin. The rash develops into blisters which eventually deaden the skin top layer and causing shedding of the skin. It is considered dangerous because it causes substantial skin loss, exposing immature skin. It is seriously painful and allows more infection to enter the skin.

The oral form may have side effects, too such as nausea, diarrhea, vomiting or upset stomach although there is no cause for alarm.

Because antibiotics are used not as a single-dose for angular cheilitis treatment, Nystatin must be stored in its original container with lid tightly closed. Refrigerate the cream formula but do not allow freezing. This will ensure that the antibiotic will retain its potency for several days of usage.

Angular Cheilitis Home Remedies

There are times when medical treatment seems not enough to treat some Illness and it’s time to go natural. You can start treatment of cold sores using angular cheilitis home remedies. Many of these have been tried and proven to offer relief in alleviating the symptom of cheilitis.

Because you’ll be preparing home remedies, you must wash your hands thoroughly  before applying any natural concoction on the areas affected. This is to ensure that no  bacteria will be added to the lesions and aggravate the condition.


An angular cheilitis home remedy that many people recommend is cucumber. You can use it in your dishes and in some beauty rituals. It can also alleviate the pain and burning sensation in the lips associated with cheilitis.

Cucumber has smooth, cooling, and softening effects on the skin. Slice a cucumber into small pieces and gently rub them on the lips and other affected areas.

Baking soda

Use baking soda. You can simply put a pinch of baking soda on the lesions then leave it for some time there. You can also make a paste by adding water to baking soda and mix it well. With this method, you can cover almost all the areas affected. Wash it off with lukewarm water. It helps in alleviating the irritation and helps in softening the skin so it will not crack any further.


The use of neem leaves as a home remedy has been written. Neem leaves have anti-inflammatory properties similar to that of cortisone and phenyl butazone. They are also good pain relievers.

Neem oil is considered a good moisturizer, helps heal skin lesions and lessens irritation caused by the disease. Application of neem leaves powder or neem oil in the areas affected can relieve you from cheilitis because of their natural healing properties.

Aloe vera

Aloe vera gel when applied to the lips and rims of the mouth helps moisturize those areas. This gel is obtained by splitting the aloe vera leaf into two and when you open it up, there you will find a colorless, odorless, tasteless and kind of slimy gel. The aloe vera gel can also be applied to skin lesions, although it is recommended to use a small amount initially for the first-time users to ensure that you do not have any allergy to this plant. This gel should be applied for 10 to 15 minutes only then rinsed off with warm water and may be done several times a day.

Virgin coconut oil

Another natural remedy to relieve the symptoms of angular cheilitis is the use of virgin coconut oil. It is claimed as an effective moisturizer. By applying it to your lips and mouth, it will prevent further cracking and drying up of the skin. A small amount of virgin coconut oil may be applied to these areas many times a day.

Angular cheilitis home remedies will help you deal with the symptoms brought about by this condition. These are alternative methods that you can use if the medical approach is not working out for you. But, if at any point during the course of treatment you notice worsening of the condition, then immediately you should stop it. Just remember, use a little at first then gradually increase the application of these substances to help your skin adapt to them.

Angular Cheilitis Treatment

What do you do when you suffer from a certain illness? Well, initially you try to find cure yourself and self-medicate. You might take medications that you think are right for your condition based on its symptoms.

Sometimes you research, ask other people about it, and eventually seek the help of a real medical doctor when it seems you cannot solve it yourself. In this article, let us discuss angular cheilitis treatment section by section.

First of all, let us make use of the pharmacological aspect of treatment.

Angular cheilitis treatment includes the use of antifungal medications because some of the microorganisms involve in its development are fungi.

A doctor may prescribe nystatin, mycostatin, and econazole to treat it.

Application of hydrocortisone topical cream may be recommended to decrease inflammation in the area, although proper application should be instructed by a medical practitioner.

Some dermatologists also encourage the application of topical cream or gel composed of antifungal and steroid to enhance drying up of the area.

Oral supplements such as iron and Vitamin B may also be advised to be taken so as to make the treatment more effective, if nutritional deficiency is the underlying cause.

Another angular cheilitis treatment requires some life-style modifications. Since the area involved is dry and needs moisture, it is recommended to drink a lot of water. Application of moisturizing cream should not be done because it will only create an environment conducive for the bacterial growth and development. Drinking a lot of water will hydrate, moisturize and bring back skin elasticity to prevent further cracking of the skin in that area. Also, eating foods rich in iron and Vitamin B will help such as green leafy vegetables, peanuts, meat, cabbage, potatoes, and bananas. If you are a smoker, then might as well stop for now or until the problem has resolved because it may contribute in aggravating the problem.

If the problem of drying and chapping of lips has just started or if you noticed that you tend to do lip licking quite often, it is advisable that you bring lip balms and creams with you. The truth is, when you lick your lips to moisten it, it actually dries it up more and puts more bacteria in the area since our tongue and saliva are also full of microorganisms that we are not aware of.

If the cause of the problem is due to poorly fitting dentures, then a visit to the dentist may help along with other above-mentioned angular cheilitis treatment. On the other hand, if it is found out that the culprit is hypervitaminosis A, and then you may want to cut down on your consumption of Vitamin A-rich foods such as sweet potato, carrots, spinach, and cod liver oil.

In order for the angular cheilitis treatment to be effective, the causative factor should be investigated first, so that a proper approach will be implemented. It won’t be long until you can smile, eat, laugh and talk again as much as you want. The key is to be patient and compliant to its treatment.